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Merck Index, The Imatge de diagramació

Farmacopees i d'altres obres de referència

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Description


  • Includes both The Merck Index 14th Edition Book and CD-ROM and The Merck Index 14th Edition/Chemists. Combines the power of the CD-ROM version of the Merck Index with the capability to do structured searches.
  • A one-volume encyclopedia of chemicals, drugs and biologicals that contains more than 10,000 monographs, 32 supplemental tables, 450 Organic Name Reactions.
  • About 4,000 of the entries cover drugs and pharmaceuticals, 2,000 describe common organic chemicals and laboratory reagents, another 2,000 cover naturally occurring substances and plants, 1,000 focus on the elements and on inorganic chemicals, and approximately 1,000 pertain to compounds of agricultural significance.
  • Each monograph in this authoritative reference source is a concise description of a single substance or a small group of closely related compounds. In addition, there are more than 700 new and completely revised monographs, thousands of new references, trademarks and uses added to previous edition's monographs. Several hundred discuss endogenous substances and biological agents.
  • There is an expanded focus on "Green Chemistry" and compounds of environmental significance. In addition to revisions and updating, enhancements include embedding the Chemical Abstracts Registry Numbers for title and derivative compounds within the monographs.

Contents


Compounds Included:

  • Human and veterinary drugs
  • Biotech drugs and monoclonal antibodies
  • Substances used for medical imaging
  • Biologicals and natural products
  • Plant and herbal medicines
  • Nutraceuticals and cosmeceuticals
  • Laboratory reagents and catalysts
  • Dyes, colors and indicators
  • Environmentally significant substances
  • Food additives and supplements
  • Flavors and fragrances
  • Agricultural chemicals, pesticides and herbicides
  • Industrial and specialty chemicals
  • Organic chemicals used in research

Information Provided:

  • Chemical, common and generic names
  • Over 15,000 trademarks and associated companies
  • CAS Registry Numbers for over 12,000 compounds
  • Over 8,500 chemical structures
  • Molecular formulae, weights and percentage composition
  • Capsule statements identifying compound classes and scientific significance
  • Scientific and patent literature references
  • Physical and toxicity data
  • Therapeutic and commercial uses
  • Caution and hazard information
  • Recalculated molecular weights using the 2005 IUPAC Table of Standard Atomic Weights
  • Up-to-date U.S. regulatory information on carcinogens and controlled substances
  • Extensively revised supplemental tables now including Acronyms, Vaccines, and Physical Constants

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Features of the CD:

  • Searchable by keywords, references, and numerical properties
  • Search the complete contents of the 14th edition, plus nearly a thousand monographs archived from previous editions
  • Comes with a free one-year subscription to the Merck Index Internet Edition
  • Windows-compatible, powered by CambridgeSoft's ChemFinder
  • Extensively revised supplemental tables now including acronyms, vaccines, and physical constants
  • More than 70 pages of hard to find information in one easy-to-use place

This product adds powerful structure searching capability to the CD included with The Merck Index 14th Edition book. The Merck Index 14th Edition/Chemists provides the user with the ability to find molecules by fragment, sub- or full structures for similarity or exact matching. Structure searching is precise and convenient and includes tautomeric full- and substructure searching. Structured searching finds matches using any of three modalities:

  • Search type (Normal/Exact/Similar)
  • Structure mode (fragment, sub- or full structure)
  • Bond type (Aromatic, Any, Tautomeric, S/D, D/A, S/A, etc.)

You can search for structures containing isotopic labels, or tetrahedral stereocenters, or other characteristics. The Merck Index 14th Edition/Chemists powers your ability to search for alternative groups, either in atom labels such as "(OH,H,CONH2,Me)" or drawn using the R-Group features of ChemDraw. Link nodes are supported, so you can search for variable-length rings and chains such as "(-CH2)6-8-" or multi-connected variables ("-R-"). You can now search for any type of single atom ("A, Q, X, M") or any group ("R").

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